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The current paper, published in 2024 by Ajla Hodzic Kuerec and colleagues, examines the relationship between NMN supplement dosage and blood NAD levels. NMN is a precursor of NAD and is known to increase NAD levels, which decline with age. The study revealed that there are significant individual differences in the effects of NMN. Let’s take a look at the study to see what research has been done to find the optimal intake for you.

Paper Information

Towards personalized nicotinamide mononucleotide (NMN) supplementation: Nicotinamide adenine dinucleotide (NAD) concentration
Title: Optimal intake of NMN supplementation focusing on individual differences
Journal: Mechanisms of Ageing and Development
This study examined the relationship between NMN supplement intake and blood NAD concentration. 80 healthy adults aged 40-65 years received placebo, 300 mg, 600 mg, or 900 mg of NMN per day for 60 days. Results showed that blood NAD concentrations increased with NMN intake, with large individual differences; increased NAD concentrations were associated with improved 6-minute walk test results and SF-36 scores.

What the latest study reveals.

The latest study, published in 2024, examined the relationship between NMN supplement intake and blood NAD levels in 80 healthy adults ages 40-65. Participants were randomly assigned to either a placebo group, a 300 mg daily group, a 600 mg group, or a 900 mg group, and took NMN for 60 days. The results showed that the NAD concentration in blood increased significantly with dose in the NMN intake group, but that there was a great deal of individual variation. The extent of the increase in NAD concentration was also associated with the results of physical fitness tests and the degree of improvement in quality of life indices.

Considerations by an OEM Company of NMN Supplements

This study is significant in that it clearly demonstrates that there are significant individual differences in the effectiveness of NMN supplements. Determining the optimal dosage for each individual by measuring blood NAD levels, rather than a uniform dosage regimen, will be the key to maximizing the effects of supplements. since NMN is a water-soluble vitamin, NMN that cannot be absorbed by the body is passed through the urine, like vitamin C. Therefore, the amount of NMN taken varies depending on the client’s intentions for the product development they wish to have made, but at ZaaZ, an NMN OEM, we take 1000 mg of NMN per day. However, future verification with a larger sample size and research on long-term effects will be required. Also, synergistic effects between NMN supplements and other health practices need to be clarified. NMN is a promising anti-aging ingredient, but establishing appropriate evidence-based usage is essential to fully realize its benefits.

Summary.

NMN supplementation may help reduce age-related declines in NAD levels and improve physical fitness and quality of life. However, the latest research has shown that the effects of NMN vary widely from person to person; NMN is a water-soluble vitamin, so NMN that is not absorbed by the body is eliminated in the urine, similar to vitamin C. The amount of NMN taken varies depending on the client’s intentions, but for your information, NMN For your reference, ZaaZ, an OEM, takes 1000 mg of NMN daily every morning.

In order to maximize the anti-aging effect of NMN, it is important to adjust the dosage according to the individual while measuring the NAD concentration in the blood. Further validation with larger sample sizes and investigation of long-term effects are needed; NMN is a promising anti-aging ingredient, but accumulating evidence and establishing appropriate usage are essential to fully realize its benefits.

Author Profile.

Ichiro Aizawa
AI writer with over 15 years of experience in the supplement industry. He is especially familiar with supplements related to anti-aging and healthy longevity. He specializes in writing easy-to-understand articles based on the latest research trends, and strives to create articles that combine AI’s unique perspective with efficient information gathering through the use of employees working for an OEM company of NMN supplements.